A simple question can easily be replied positively to guide someone towards the right way to fish. fish-a-holic is obviously new to the Vedder (am I correct?) and looking for information on fishing locations to start with. The area around Keith Wilson Bridge is visible, closest to Hwy 1, therefore new anglers have a tendency to crowd around there.
So, here's the information you are looking for. I may miss some items but other locals will fill those in.
Keith Wilson Bridge is located near the lower end of the Vedder River. That section of the river is actually known as the Vedder Canal. Don't be deceived by the straight waterway. Just underneath the water, shallow gravel bars sit beside deeper channels where fish would travel.
Because of its proximity to the Fraser River, fresh fish usually swim up very fast once they enter. The area is also tidal influenced. During a good high tide, you can often witness schools of salmon moving up at a very fast pace. This is quite a contrast to the section further upstream, where fish would actually sit at certain spots during the day.
Because they are so aggressive, fish that just enter the river are also eager biters. You can basically float fish with freshly cured roe, or equip yourself with a medium spincasting setup and toss spoons or spinners all day. During September, pink salmon (during odd years) and coho salmon will move through here. Around late September, white chinook salmon will show up. In October and November, you'll find schools of chinook, coho and chum salmon moving through. Between January and April, the area can also be good for steelhead at times. This time of the year, you may want to try flyfishing for trout.
Plan your trip so that it coincides with a high tide or first light. Spend some time scouting around the area and seek for deep slots of water where fish can hide or travel. Try not to join the crowd because many anglers do not usually indicate good fishing. In fact, with so many people around, most fish are probably spooked.
The area just under Keith Wilson Bridge is quite deep due to the man-made structure. This creates a brief resting hole for the fish that just enter the river. During September and October, you'll often find people lining up along the bar and trying to catch one. Unfortunately when there are too many fish stacking up at one place, most fish usually end up being foul hooked.
If you get a chance, head up to Lickman Road parking lot and walk along the Rotary trail as well. You'll find lots of good spots this way.